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Because estrogen E and T are the major sex steroids in women and men, respectively, the traditional view had been revew E revview regulated bone turnover in women and T played the analogous role in men. The description of ER- deficient and Free Ballarat christian dating males, however, initiated a major shift in our thinking on the relative roles of T and E in regulating the male skeleton, because these individuals all had unfused epiphyses, high bone turnover, and osteopenia. Similar, albeit less striking, findings were noted in mouse models with knock-out of either the Male review Melton or the aromatase genes.

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Clinical review 144: Estrogen and the male skeleton.

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Clinical review Estrogen and the male skeleton.

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